CLINICAL TRIALS AND OBSERVATIONS Safety of anticoagulants in children with arterial ischemic stroke
نویسندگان
چکیده
1Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON; 2Department of Pediatrics, University of Toronto, Toronto, ON; 3Stroke Program, Alberta Children’s Hospital, Pediatric and Clinical Neuroscience, University of Calgary, Calgary, AB; 4Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, ON; 5Department of Medical Imaging, University of Toronto, Toronto, ON; 6Children’s Stroke Program, Division of Neurology, Department of Pediatrics; 7Division of Pediatric Emergency Medicine; and 8Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, ON; and 9Division of Pediatric Hematology/Oncology, McMaster University, Hamilton, ON
منابع مشابه
Potential impact of new oral anticoagulants on the management of atrial fibrillation-related stroke in primary care
AIM Anticoagulant prophylaxis with vitamin K antagonists (such as warfarin) is effective in reducing the risk of stroke in patients with atrial fibrillation (AF). New oral anticoagulants have emerged as potential alternatives to traditional oral agents. The purpose of this review was to summarise the effectiveness and safety of rivaroxaban, dabigatran and apixaban in stroke prevention in patien...
متن کاملNon–Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention in Asian Patients With Nonvalvular Atrial Fibrillation
Stroke prevention with vitamin K antagonists (VKAs) is essential in the management of atrial fibrillation (AF). However, it has been generally perceived that Asian patients are naturally more sensitive to VKAs and have unacceptably higher rates of intracranial hemorrhage (ICH) even when international normalized ratio is ideally maintained. Consequently, VKAs have been largely underused or under...
متن کاملCarotid endarterectomy--an expression of concern.
THE READERS OF STROKE are offered in this issue the results of a series of studies and some critical observations relating to the performance of carotid endarter-ectomy on either asymptomatic or, more importantly, symptomatic patients. Some neurologists, neurosur-geons and vascular surgeons will undoubtedly disagree with the comments made or with the conclusions reached by several, or even by a...
متن کاملSafety of dexamphetamine in acute ischemic stroke: a randomized, double-blind, controlled dose-escalation trial.
BACKGROUND AND PURPOSE Amphetamine is reported to enhance recovery after experimental stroke, but results from the first few trials in humans are inconclusive. Limited information is available on treatment safety. This study intended to investigate the safety and tolerability of dexamphetamine in patients with acute cerebral ischemia. METHODS Forty-five patients with cerebral ischemia were en...
متن کاملI-12: Objective Embryo Assessment Utility of Time-Lapse
Background Traditionally, embryo incubation and assessment daily has been under a light microscope, these observations are inevitably restricted to specific times and considering that the development of the embryo is a dynamic process, several critical stages in between observations may go unnoticed. For this reason, the new technologies, time lapse monitoring, have focused on the research for ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012